Osteoblast Autonomous P i Regulation via Pit1 Plays a Role in Bone Mineralization
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چکیده
منابع مشابه
Osteoblast autonomous Pi regulation via Pit1 plays a role in bone mineralization.
The complex pathogenesis of mineralization defects seen in inherited and/or acquired hypophosphatemic disorders suggests that local inorganic phosphate (P(i)) regulation by osteoblasts may be a rate-limiting step in physiological bone mineralization. To test whether an osteoblast autonomous phosphate regulatory system regulates mineralization, we manipulated well-established in vivo and in vitr...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2007
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.00104-07